down syndrome
NounOpen English WordNet
Noun (1)
- a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardationSynonyms: mongolismmongolianismDown's syndrometrisomy 21Type of trisomy, birth defect
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Webster's Dictionary (1913)
Down′ syn′drome, Down's′ syn′drome noun
Medicine A congenital disorder caused by an extra chromosome 21 in some or all cells. It causes a variable number and degree of abnormalities, including retarded growth, mental retardation, a short nose, prominent epicanthic folds on the eyelids, a protruding lower lip, and other physical features having varying degrees of deviation from the normal. Called also mongolism, trisomy-21 and trisomy 21 syndrome.
Webster’s Revised Unabridged Dictionary (1913), from GCIDE 0.54 · with additions: GCIDE editors